Proferrin ES- 10.5mg of high Absorbing Heme Iron Polypeptide. Made in the USA. 90 Tablets. Easy on the Gut. Not affected by Coffee, Calcium, or PPI's. Review
Our verdict
A premium heme-iron tablet aimed at people who want a gentler-on-the-gut alternative to standard iron salts, at a noticeably higher price point.
Check price on AmazonBest for
People who have had trouble tolerating conventional iron supplements and are looking for a heme-based alternative made in the USA.
Skip if
You're working with a tight supplement budget, since this costs considerably more per tablet than typical ferrous sulfate or ferrous gluconate products.
- Form Tablets
- Count 90 Count
- Flavor Unflavored
- Type Iron
- Diet Gluten Free
- Benefits Iron Support
- Priced 234% above the category median ($17.19 across 59 tracked models)
Pros
- Heme iron polypeptide form marketed as gentle on the digestive system
- Maker states it's not affected by coffee, calcium, or PPI medications, unlike some iron forms
- Made in the USA
- Gluten free formula
Cons
- Significantly more expensive per tablet than standard ferrous sulfate or ferrous gluconate options
- Lower elemental iron per tablet (10.5mg) than many ferrous sulfate products, which may mean more tablets are needed to reach a comparable dose
- Smaller bottle size at 90 tablets
Our scorecard
-
Owner rating4.5/5
4.5 average across 1,200 owner ratings
-
Popularity1.7/5
1,200 owner reviews, fewer than most models here
The overall score is owner satisfaction weighted by how many reviews back it, so a high rating from few reviews counts for less. The bars below show where this model stands against the other home health monitors: bathroom scales, blood pressure monitors, pregnancy and ovulation tests, thermometers, body composition monitors, stethoscopes, glucose monitors and pulse oximeters we track in this category on price, popularity and size. Context, not marks against it, and our read of the data, not a lab test.
Overview
['Proferrin ES is built around heme iron polypeptide, a form of iron derived differently from the ferrous salts found in most drugstore iron pills. Each tablet supplies 10.5mg of heme iron, and the maker markets it as easy on the gut and as not being affected by coffee, calcium, or proton pump inhibitors (PPIs), factors that can interfere with absorption of some other iron forms.', "The product ships as 90 unflavored tablets and is made in the USA. It's labeled gluten free, which is helpful for shoppers managing gluten sensitivities alongside low iron concerns.", 'This is a specialty product, and the price reflects that positioning. At 4.5 stars across about 1,200 reviews, with roughly 1,000 units purchased in the past month, it has built a loyal following, particularly among people who found other iron forms hard to tolerate. As always, check with a healthcare professional before adding any iron supplement to your routine.']
Specifications
| Form | Tablets |
|---|---|
| Count | 90 Count |
| Flavor | Unflavored |
| Type | Iron |
| Diet | Gluten Free |
| Benefits | Iron Support |
| Allergens | Gluten Free |
Performance notes
Each tablet delivers 10.5mg of heme iron polypeptide in unflavored, easy-to-swallow form, with 90 tablets per bottle. The maker highlights that this form is designed to be gentle on the gut and is marketed as unaffected by coffee, calcium, or PPI medications, unlike some iron salts that can interact with these.
What buyers say
A 4.5 star rating from about 1,200 reviews and roughly 1,000 units bought monthly points to a smaller but dedicated customer base, likely people who sought out this form after struggling with other iron supplements.
Similar home health monitors: bathroom scales, blood pressure monitors, pregnancy and ovulation tests, thermometers, body composition monitors, stethoscopes, glucose monitors and pulse oximeters to consider
- Slow
Slow Fe 45mg Iron Supplement for Iron Deficiency, Slow Release, High Potency, Easy to Swallow Tablets - 60 Count
$18.9710,000+ bought last monthView on Amazon - Slow
Slow Fe 45mg Iron Supplement for Iron Deficiency, Slow Release, High Potency, Easy to Swallow Tablets - 30 Count
$8.974,000+ bought last monthView on Amazon
Frequently asked questions
What makes heme iron different from other iron supplements?
Heme iron polypeptide is derived from a different source than the ferrous salts (like ferrous sulfate or gluconate) used in most iron pills. The maker markets it as gentler on the stomach and less affected by dietary factors like coffee or calcium.
Why does this cost more than other iron supplements?
Heme iron polypeptide products are generally priced higher than standard ferrous salt supplements due to the different sourcing and manufacturing process. Shoppers on a budget may want to compare cost per elemental milligram of iron.
Is 10.5mg of iron enough per tablet?
That depends on individual needs, which is why it's best to discuss appropriate dosing with a healthcare professional rather than deciding based on the label alone.